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Photo: Motorcade of Kamala Harris' Husband Blocks Handicapped Parking Spots During His Shopping Run_我的网站

A |     阿尔茨海默病（AD）是一种使人衰弱的渐进性疾病，开始时是轻微的记忆丧失，慢慢地破坏了认知功能和记忆。

B |     The husband of Vice President Kamala Harris, Doug Emhoff, went shopping at a Whole Foods Market in California, blocking several parking places designated for people with disabilities as he shopped, the New York Post reported.,According to the report, the second gentleman engaged in some rather inconsiderate behavior outside the grocery store in Brentwood as he spent approximately 20 minutes browsing the aisles before returning with two bags of supplies.,New images from Emhoff's visit to the market on Wednesday show two Secret Service cars positioned diagonally over the specified areas.,According to California Vehicle Code, without a specific identifying license plate or placard visible, "it is unlawful for any person to park or leave standing any vehicle in a stall or space designated for disabled persons and disabled veterans.",However, neither car reportedly had the required identification visible to the public. The Department of Homeland Security-issued "US Government...For Official Use Only" license plates were supposedly spotted on the black Chevrolet Suburbans instead.,Emhoff was earlier observed picking up dry cleaning that day close to the supermarket. According to the report, one of the vehicles momentarily activated its lights and sirens as the motorcade exited the parking area towards Whole Foods.,Earlier, on the anniversary of the signing of the Americans with Disabilities Act, Vice President Kamala Harris participated in a roundtable discussion with a number of stalwarts in the disability rights movement.,In a Medicare for All proposal during her failed campaign for president, Harris attempted to guarantee that individuals with disabilities had equal access to employment opportunities, education, housing and health care.,I Am Woman: Netizens Mock Kamala Harris for Outlandish Greeting and Use of Gender Pronouns27 July, 11:11 GMT。它目前没有治愈方法，预计到2050年将影响全球1亿多人。

C | 在美国，根据国家老龄化研究所的数据，AD是老年人痴呆的主要原因，也是第七大最常见的死亡原因。

D | 正在进行的阿尔茨海默氏症研究集中在两个关键的神经毒性蛋白上：淀粉样β（Aβ）和tau。

E | 尽管这些蛋白质已被证明与AD有关，但Aβ和tau的水平并不能持续解释或与一些疾病患者的认知能力下降的严重程度相关。作为麻省总医院布里格姆医疗系统的创始成员之一，布里格姆妇女医院的研究人员着手确定其他可能直接参与AD基本方面的蛋白质，如突触损失和神经变性。他们将实验室的神经元暴露在大约40人的大脑提取物中，这些人要么患有AD，要么在Aβ和tau水平较高的情况下受到保护，要么在大脑中很少或没有Aβ和tau时受到保护。

F | 科学家们发现并验证了神经节苷脂GM2激活剂（GM2A）是一种能够减少神经元发射并诱发神经元完整性丧失的蛋白质。这些蛋白质的特征可能有助于AD的病因、疾病的进展，或两者都有。高级作者、神经学系的Tracy Young-Pearse博士说："我们的数据有助于确定一种可能与阿尔茨海默病的发病机制有关的新的和潜在的重要蛋白质。有趣的是，GM2A以前被认为是一种与Tay-Sachs病非常相似的溶酶体储存障碍的致病因素，Tay-Sachs病是另一种像AD一样破坏神经元的疾病。

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